Polysaccharide-coated iron oxide nanoparticles: Synthesis, properties, surface modification

Stolyar, S. V.; Krasitskaya, V. V.; Frank, L. A.; Yaroslavtsev, R. N.; Chekanova, L. A.; et al. Materials Letters. https://doi.org/10.1016/j.matlet.2020.128920

In this work, magnetite nanoparticles coated with polysaccharides were synthesized. Arabinogalactan and chitosan were used as polysaccharides. The possibilities of immobilization of biospecific molecules on the surface of the obtained composites were studied. Experiments on covalent immobilization of biospecific molecules on magnetic nanoparticles coated with a polysaccharide showed a high density of immobilized molecules. This suggests the use of such materials in bioanalytical systems or as affinity sorbents.