CRYSTAL STRUCTURE OF NORFLOXACINIUM AND 2,2 '-BIPYRIDYL-1 '-IUM 2-THIOBARBITURATES

Golovnev, N. N.; Molokeev, M. S.; Sterkhova, I., V; Lesnikov, M. K. Journal Of Structural Chemistry.

Organic salts with the composition NfH2(Htba)·6H2O (I) and BipyH(Htba)·2H2O (II) (Н2tba is 2-thiobarbituric acid, NfH is norfloxacin and Bipy is 2,2′-dipyridyl) are prepared. Their structures are determined by XRD (CCDC cif-file No. 1967494-1967495). Crystals I are triclinic: a = 11.8821(4) Å, b = 11.9959(5) Å, c = 12.0038(4) Å, α = 119.835(1)°, β = 107.691(1)°, γ = 95.237(1)°, V = 1351.80(9) Å3, space group P-1, Z = 2. Crystals II are monoclinic: a = 7.9587(2) Å, b = 19.6272(4) Å, c = 10.1118(2) Å, β = 98.118(1)°, V = 1563.71(6) Å3, space group P21/nZ = 4. The structures are stabilized by numerous hydrogen bonds and π–π interactions involving НtbaNfH+2NfH2+, and BipyH+ ions. Thermal decomposition of these compounds in air includes dehydration and oxidative degradation stages.