N-Isopropyl-N′,N′-diorganyl-N-(silylmethyl)ureas: synthesis, structure, and biological activity

https://doi.org/10.1007/s11172-024-4672-1

The method for the synthesis of N-isopropyl-N′,N′-diorganyl-N-[(triethoxysilyl)-methyl]ureas was optimized. The reaction of these compounds with triethanolamine afforded the corresponding N-(silatranylmethyl)ureas R₂NC(O)N(Prⁱ)CH₂Si(OCH₂CH₂)₃N (R = Me, Ph). The structures of the new compounds were confirmed by multinuclear NMR spectroscopy. The structure of the silane Ph₂NC(O)N(Prⁱ)CH₂Si(OEt)₃ was established by X-ray diffraction. Preliminary data on the effect of N-isopropyl-N′,N′-dimethyl-N-(silatranylmethyl)urea on the parameters of the rapeseed and wheat growth were obtained.